Figure 8.

Percent mineralization based on histomorphometric analysis of Von Kossa stain of beads on days 1, 7, 14, and 21. Highest mineralization can be observed on day 21 in the inner annuli of bioreactor cultured beads. The outer annuli of bioreactor cultured beads and statically cultured small beads almost exhibit high mineralization on day 21. The symbols (*, #, +) indicate statistical significance within a timepoint (p < 0.05). Groups with symbol *, #, or + are statistically different from all groups except those groups with the same symbol. Groups with the same symbol are statistically similar to each other.