Table 3.
Univariate | Multivariate* | |||||
---|---|---|---|---|---|---|
Retinal Vessel Caliber§ | n | Any CVD (%) | OR (95% CI) | p-value† | OR (95% CI) | p-value† |
Arteriole diameter, All patients | ||||||
1st Quartile (Lowest | 399 | 133 (33.3%) | 1.00 | 0.69 | 1.00 | 0.25 |
2nd Quartile | 400 | 124 | (31.0%) | 0.90 (0.67 - 1.21) | 0.82 (0.58 - 1.14) | |
3rd Quartile | 400 | 121 (30.3%) | 0.87 (0.64 - 1.17) | 0.90 (0.64 - 1.27) | ||
4th Quartile (Highest) | 400 | 140 (35.0%) | 1.08 (0.80 - 1.44) | 1.19 (0.85 - 1.69) | ||
Vein diameter, All patients | ||||||
1st Quartile | 399 | 129 (32.3%) | 1.00 | 0.02 | 1.00 | 0.01 |
2nd Quartile | 400 | 107 (26.8%) | 0.76 (0.56 - 1.04) | 0.87 (0.61 - 1.23) | ||
3rd Quartile | 400 | 127 (31.8%) | 0.97 (0.72 - 1.31) | 1.15 (0.82 - 1.62) | ||
4th Quartile | 400 | 155 (38.8%) | 1.32 (0.99 - 1.77) | 1.47 (1.03 - 2.08) | ||
Arteriole diameter, Diabetic patients | ||||||
1st Quartile | 148 | 77 (52.0%) | 1.00 | 0.28 | 1.00 | 0.48 |
2nd Quartile | 167 | 66 (39.5%) | 0.60 (0.39 - 0.94) | 0.51 (0.31 - 0.84) | ||
3rd Quartile | 163 | 61 (37.4%) | 0.55 (0.35 - 0.87) | 0.58 (0.35 - 0.96) | ||
4th Quartile | 189 | 88 (46.6%) | 0.80 (0.52 - 1.24) | 0.80 (0.49 - 1.31) | ||
Vein diameter, Diabetic patients | ||||||
1st Quartile | 152 | 68 (44.7%) | 1.00 | 0.25 | 1.00 | 0.10 |
2nd Quartile | 139 | 51 (36.7%) | 0.72 (0.45 - 1.15) | 0.74 (0.44 - 1.23) | ||
3rd Quartile | 176 | 74 (42.0%) | 0.90 (0.58 - 1.39) | 1.03 (0.63 - 1.66) | ||
4th Quartile | 200 | 99 (49.5%) | 1.21 (0.79 - 1.85) | 1.38 (0.85 - 2.26) |
CVD=Cardiovascular disease. OR=Odds ratio. CI=Confidence interval.
Based on mean of both eyes
p-value is for test of linear trend
Adjusted by Age, Sex, Low-density Lipoprotein, High-density Lipoprotein, Systolic blood pressure, Smoking Status, Diabetes, Hypertension, Hemoglobin A1C, Triglycerides, eGFR, and log of 24H Urine Protein