Table 1.
Strain | Na | Phase lb | Phase 2c | Baselined | |
---|---|---|---|---|---|
MALDR | Male | 9 | 5.44 ± 0.73 | 5.00 ± 0.68 | 19.00 ± 0.94 |
Female | 12 | 5.75 ± 0.63 | 2.75 ± 0.58 | 20.33 ± 0.82 | |
MAHDR | Male | 11 | 6.00 ± 0.66 | 4.18 ± 0.61 | 20.64 ± 0.85 |
Female | 9 | 5.00 ± 0.73 | 3.22 ± 0.67 | 21.44 ± 0.94 | |
MALSENS | Male | 12 | 2.58 ± 0.56 | 2.00 ± 0.71 | 28.33 ± 1.72 |
Female | 14 | 3.00 ± 0.52 | 2.14 ± 0.65 | 28.79 ± 1.59 | |
MAHSENS | Male | 11 | 4.18 ± 0.59 | 2.91 ± 0.74 | 28.55 ± 1.80 |
Female | 13 | 4.92 ± 0.54 | 5.46 ± 0.68 | 23.62 ± 1.65 |
Notes.
Mice that failed to acquire the task at any training phase are excluded (see Results section for number of failures).
During Phase 1 there were 60 Go trials and 0 No-Go trials. Each Go cue lasted for 30 seconds. Mice advanced to the Phase 2 of training by responding on at least 30 of the 60 Go trials within 40 minutes for two consecutive sessions. MALSENS mice advanced after fewer sessions that the MAHSENS mice (F(1, 46) = 10.19,p = .003.) No other differences were found.
During Phase 2 the Go cue was shortened to 10 s, and mice again had to respond on at least 30 of 60 Go trials within 40 minutes for two consecutive sessions. Again, MALSENS mice advanced more quickly than MAHSENS mice (F(1, 46) = 9.24, p = .004.)
The baseline phase consisted of 30 Go trials and 30 No-go trials (see Procedure for full description). Mice attained stable behavior at similar rates, and no significant line differences were observed.