Figure 3.

Characterization of the Different Oligomeric Species Formed during αS Aggregation and Fibril Formation

(A) The time dependence of the mass fraction of the four oligomeric distributions A_small (red squares), A_medium (orange circles), B_medium (green triangles), and B_large (blue triangles). The data shown correspond to the average and standard error of five different experiments.

(B) Proteinase K degradation curves of the different protein species (monomer in red, type A oligomer in orange, type B oligomer in blue, and fibrils in black). The data shown here correspond to the average and standard error of three different experiments. See also Figure S3.