Rnd2 and Rnd3 Cannot Replace Each Other in Migrating Neurons
(A) The radial migration defect of Rnd3-deficient neurons was rescued by overexpression of a shRNA-resistant version of Rnd3 (Rnd3∗), but not by overexpression of Rnd2. Mean ± SEM; one-way ANOVA followed by a Fisher's PLSD post hoc test; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
(B) The migration defect of Rnd2-silenced neurons was rescued by overexpression of Rnd2∗, but not of Rnd3. Mean ± SEM; one-way ANOVA followed by a Fisher's PLSD post hoc test; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Scale bars represent 100 μm (A, B).