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. 2012 May 16;109(23):9219. doi: 10.1073/pnas.1207087109

Fig. A.

Fig. A.

Anterograde pattern of spread of VSV (VSV-G) from a virus stock derived from a purified plaque. Anterograde transmission was tested by injection into the vitreous body of the eye. (A) A diagram of a parasaggital section of the brain illustrates the expected pattern of transmission for an anterograde transsynaptic virus injected into the eye. It would be expected to label several brain centers involved in visual processing, including the lateral geniculate nucleus (LGN) and visual cortex area 1 (V1). The red arrow indicates the path of the retinal ganglion cell axons to their direct targets, the cells of the LGN. The blue arrow indicates the path of the LGN axons to their V1 targets. The green needle indicates the injection site. (B) A parasaggital section from an injected brain at 7 d post infection, showing labeling of the LGN and V1. All injections that gave brain labeling using this virus stock showed a similar pattern (5/10 animals injected).