Table 2.

ID event types and their arguments

Type	Core arguments	Additional arguments
GENE EXPRESSION	Theme(PROTEIN or REGULON-OPERON)
TRANSCRIPTION	Theme(PROTEIN or REGULON-OPERON)
PROTEIN CATABOLISM	Theme(PROTEIN)
PHOSPHORYLATION	Theme(PROTEIN)	Site(ENTITY)
LOCALIZATION	Theme(Core entity)	AtLoc(ENTITY), ToLoc(ENTITY)
BINDING	Theme(Core entity)+	Site(ENTITY)+
PROCESS	Participant(Core entity)?
REGULATION	Theme(Core entity/Event), Cause(Core entity/Event)?	Site(ENTITY), CSite(ENTITY)
POSITIVE REGULATION	Theme(Core entity/Event), Cause(Core entity/Event)?	Site(ENTITY), CSite(ENTITY)
NEGATIVE REGULATION	Theme(Core entity/Event), Cause(Core entity/Event)?	Site(ENTITY), CSite(ENTITY)

The type of entity allowed as argument is specified in parenthesis. "Core entity" is any of PROTEIN, TWO-COMPONENT-SYSTEM, REGULON-OPERON, CHEMICAL, or ORGANISM. Arguments that can be filled multiple times marked with "+", non-mandatory core arguments with "?" (all additional arguments are non-mandatory).