Table 5: Incidence Density for Episodes of Influenza-Related ARI and Episodes Requiring Hospitalization – Vaccine Versus Placebo*.
| COPD Severity | All Episodes of Influenza-Related ARI/100 Person-Years RR (95% CI) |
P Value | All Episodes of Influenza-Related ARI That Required Hospitalization/100 Person-Years RR (95% CI) |
P value |
|---|---|---|---|---|
| All patients | Vaccine: 6.8 Placebo: 28.1 0.2 (0.06−0.70) |
0.005 | Vaccine: 3.4 Placebo: 8.3 0.4 (0.04−2.50) |
0.3 |
| Mild | Vaccine: 4.5 Placebo: 28.2 0.2 (0.003−1.30) |
0.06 | Vaccine: 4.5 Placebo: 9.4 0.5 (0.01−9.30) |
0.6 |
| Moderate | Vaccine: 13.2 Placebo: 23.8 0.5 (0.05−3.80) |
0.5 | Vaccine: 0 Placebo: 5.9 0 (0.00−43.10) |
0.5 |
| Severe | Vaccine: 4.6 Placebo: 31.2 0.1 (0.003−1.10) |
0.04 | Vaccine: 3.4 Placebo: 8.3 0.5 (0.01−10.00) |
0.6 |
*
Abbreviations: ARI, acute respiratory illness; CI, confidence interval; COPD, chronic obstructive pulmonary disease; RR, relative risk. Source: Wongsurakiat et al, 2004 (35)