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. 2012 May 23;92(1):112–117. doi: 10.1038/clpt.2012.57

Table 1.

Assignment of likely SLCO1B1 phenotype based on genotype

Genotype definitions Diplotypes observed Genotype at rs4149056 Observed phenotype
An individual carrying two functional alleles *1/*1 TT Homozygous wild-type or normal (55–88% of patients) high activity
An individual carrying one functional allele plus one reduced-function allele *1/*5 (or *1/*15, *1/*16, or *1/*17) TC Heterozygous (11–36% of patients) intermediate activity
An individual carrying two reduced-function alleles *5/*5 (or *5/*15, *5/*16, *5/*17, *15/*15, *15/*16, *15/*17, *16/*16, *16/*17, or *17/*17) CC Homozygous variant or mutant (0–6% of patients) low activity