Table 6.

Ten most up-regulated pathways by insulin in the insulin-resistant group

GO category	Pathway name	Nominal p	Permuted p
GO:0016125	sterol metabolic process	1.52E-08	0.0001
GO:0006629	lipid metabolic process	2.31E-08	0.0001
GO:0008203	cholesterol metabolic process	1.12E-07	0.0001
GO:0044255	cellular lipid metabolic process	1.36E-07	0.0001
GO:0008202	steroid metabolic process	6.34E-07	0.0001
GO:0016126	sterol biosynthetic process	4.45E-06	0.0002
GO:0006694	steroid biosynthetic process	4.93E-06	0.0001
GO:0001889	liver development	6.62E-06	0.0002
GO:0008015	blood circulation	1.00E-05	0.0002
GO:0042127	regulation of cell proliferation	1.77E-05	0.0006