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. 2012 Apr 1;9(4):437–445. doi: 10.4161/rna.20480

Table 1b. Five sRNAs involved in virulence of S. Typhimurium.

sRNA name Target mRNA Role in virulence References
IsrJ
 
Control of effector protein production
32
IsrM
hilE, sopA
Modulates the expression of SPI1 proteins via hilE;
downregulates SopA
57
IstR
tisAB
SOS induced toxic peptide – Inhibits growth allowing DNA repair
62,61
OxyS
Regulates about 40 genes; including rpoS
Inhibits alternate stress adaptation pathways during oxidative stress
20,32,61
SroA Riboswitch element of the thiBPQ operon Putative import of Thiamine and Thiamine pyrophosphate 61
HHS Vulnerability Disclosure