Table 2. Safety Analysis.

	Control group(n = 39)	Dil group(n = 40)
Heart rate (beats/min)
Baseline	71.5±7.9	74.6±6.8
Follow up	71.0±7.4	69.3±6.8∧ (p<0.001)
Ejection fraction (%)
Baseline	60.5±5.6	58.6±5.1
Follow up	60.0±4.4	58.5±4.7
Creatinine (mg/dL)
Baseline	0.70±0.21	0.72±0.18
Follow up	0.71±0.21	0.74±0.18
Alanine transaminase (U/L)
Baseline	25.5±9.0	24.5±8.1
Follow up	24.8±7.4	25.8±7.1

^∧p<0.05 vs. baseline. Unpaired Student’s t test or Mann-Whitney-Test was used to compare differences in means or mean ranks of variables between control group and Dil group. Paired Student’s t test or Wilcoxon signed-rank test was used to compare the means or mean ranks of the two related samples (baseline vs. Follow up) as indicated. The Bonferroni correction was applied and adjust p-values (p value x 2) were obtained.