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. Author manuscript; available in PMC: 2012 Jun 27.
Published in final edited form as: Cancer Prev Res (Phila). 2010 Sep 21;3(10):1246–1258. doi: 10.1158/1940-6207.CAPR-10-0088

Figure 1.

Figure 1

Changes in body weight between postnatal weeks 4 and 28 in the (a) wildtype and (b) Pten+/− mice fed AIN93G based control diet containing either 18% energy from fat and 1K international units (IU) of cholecalciferol (VD3)/kg feed; vitamin D supplemented control diet containing 25K IU of VD3/kg diet; OID containing 58% fat and 1.8K UI VD3/kg diet; and vitamin D supplemented OID. When compared to control diet fed mice, OID significantly increased body weights in wildtype and Pten+/− mice (p<0.001). Body weights were also elevated in wildtype mice fed VD3 diet (p<0.008) or VD3 supplemented OID (p<0.001). Mean ± SEM of 8–12 mice per group are shown. (c) Pten protein levels, assessed using Western blot, in the mammary gland of 28-week-old wildtype and Pten+/− mice. Bars marked with a different letter are statistically significantly different from each other. Mean ± SEM of 5–7 mice per group are shown.