Table 1.
Prevalence of hepatic injury in a cohort of 232 hepatic resection samples
| Injury | Definition | Per cent (n) |
|---|---|---|
| Steatosis | ||
| Grade 0 | 0% | 24% (56) |
| 1 | >0–5% | 31% (73) |
| 2 | >5–33% | 27% (63) |
| 3 | >33–66% | 12% (27) |
| 4 | >66% | 6% (14) |
| Sinusoidal injury | ||
| Grade 0 | Nil | 70% (163) |
| 1 | up to 1/3 lobular involvement | 11% (26) |
| 2 | >1/3–2/3 lobular involvement | 10% (23) |
| 3 | >2/3 to complete lobular involvement | 9% (21) |
| Steatohepatitis | ||
| Presence | steatosis >5%, NAFLD activity scorea >2 | 4% (10) |
a
NAFLD activity score (NAS) = sum of score for Mallory bodies, lobular inflammation, hepatocyte ballooning and perisinusoidal fibrosis (each factor scored 0 = absent, 1 = focal involvement of some lobules, 2 = focal involvement of most lobules, 3 = focal involvement of most or all, with diffuse involvement of some or most).12