Table 4.
Protective efeect of Pinus roxburghii Sarg. on tail withdrawal reflex induced by tail immersion.
| Groups | Drug (dose), route | Reaction time (min) Mean ± SEM | |||
|---|---|---|---|---|---|
| 30 min | 60 min | 90 min | 120 min | ||
| Control | Tween 80 (5%), p.o | 1.0 ± 0.1 | 1.4 ± 0.2 | 1.5 ± 0.2 | 2.8 ± 0.2 |
| Standard | Diclofenac sodium (50 mg/kg), p.o | 5.8 ± 0.2** | 8.2 ± 0.2** | 8.4 ± 0.2** | 8.8 ± 0.2** |
| AB | 100 mg/kg, p.o | 1.4 ± 0.2 | 2.4 ± 0.3 | 2.8 ± 0.2 | 3.4 ± 0.2 |
| AB | 300 mg/kg, p.o | 1.8 ± 0.2 | 3.2 ± 0.2* | 4.4 ± 0.4* | 6.2 ± 1.5* |
| AB | 500 mg/kg, p.o | 2.8 ± 0.4** | 3.2 ± 0.4* | 4.6 ± 0.2* | 5.4 ± 1.9 |
n = 5. Results are expressed as mean ± SEM. *P > 0.05, **P < 0.01 as compared to control, AB = alcoholic bark extract.