Table 3.
Lenalidomide containing regimens in relapsed/refractory indolent and mantle cell lymphoma.
Author | Year | Phase | Histology | n | Age (range) | Previous CT | Combination | ORR (%) | CR (%) |
---|---|---|---|---|---|---|---|---|---|
Wang et al. [27] | 2007 | I/II | MCL | 15 | 73 (62–84) | 2 (1–7) | RL | 83∗ | 17∗ |
Dutia et al. [28] | 2009 | II | Indolent NHL | 15 | 60 (50–91) | 4 (1–11) | RL | 83.3 | 41 |
Zaja et al. [29] | 2011 | II | MCL | 33 | 68 (51–80) | 3 (2–7) | LD | 52 | 24 |
∗: data from patients enrolled in lenalidomide 20 mg/daily arm. No response was obtained for lower dosage.
CT: chemotherapy; ORR: overall response rate; CR: complete response; RL: rituximab and lenalidomide; LD: lenalidomide and dexamethasone.