Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	1794 people 4 RCTs in this analysis	Extrapyramidal symptoms with haloperidol with aripiprazole Absolute results reported graphically	RR 0.45 95% CI 0.32 to 0.64	Large effect size	aripiprazole
Systematic review	1589 people 2 RCTs in this analysis	Mean difference in weight gain (kg) with haloperidol with aripiprazole Absolute results not reported	Mean difference +0.6 kg 95% CI –0.1 kg to +1.2 kg		Not significant
Systematic review	1602 people 2 RCTs in this analysis	Sedation with haloperidol with aripiprazole Absolute results not reported	RR 0.65 95% CI 0.45 to 0.95	Small effect size	aripiprazole