Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	232 people Data from 1 RCT	Sedation 1 to 3 months 53/117 (45%) with pimozide 68/115 (59%) with standard antipsychotic drugs	RR 0.77 95% CI 0.61 to 0.98 NNT 7 95% CI 4 to 61	Small effect size	pimozide
Systematic review	192 people Data from 1 RCT	Tremor 1 to 3 months 43/97 (44%) with pimozide 27/95 (28%) with standard antipsychotic drugs	RR 1.57 95% CI 1.07 to 2.29 NNH 6 95% CI 3 to 44	Small effect size	standard antipsychotic drugs
Systematic review	56 people Data from 1 RCT	ECG changes 2/28 (7%) with pimozide 3/28 (11%) with standard antipsychotic drugs	RR 0.67 95% CI 0.10 to 3.70 The RCT may have been too small to detect a clinically important difference		Not significant