Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	40 people Data from 1 RCT	Mean difference in extrapyramidal symptoms score at endpoint short term with risperidone (4 mg/day) with zotepine (225 mg/day) Absolute results not reported	Mean difference +1.80 95% CI –0.64 to +4.24		Not significant
Systematic review	40 people Data from 1 RCT	Mean difference in extrapyramidal symptoms score at endpoint short term with risperidone (8 mg/day) with zotepine (225 mg/day) Absolute results not reported	Mean difference +2.50 95% CI –0.05 to +5.05		Not significant
Systematic review	40 people Data from 1 RCT	Use of antiparkinsonism medication short term with risperidone (4 mg/day) with zotepine (225 mg/day) Absolute results not reported	RR 6.00 95% CI 0.79 to 45.42		Not significant
Systematic review	40 people Data from 1 RCT	Use of antiparkinsonism medication short term with risperidone (8 mg/day) with zotepine (225 mg/day) Absolute results not reported	RR 3.00 95% CI 0.69 to 13.12		Not significant