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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Bone Miner Res. 2012 Feb;27(2):390–400. doi: 10.1002/jbmr.545

Fig. 1. In vitro osteoclastogenesis.

Fig. 1

Representative images of TRAP5b+ osteoclast cells in the male and female Igfbp2−/− and Igfbp2+/+ from 7 day bone marrow cultures (left and middle panels). Igfbp2−/− cultures were also treated with 200 ng/ml IGFBP-2 (right) rescuing the null phenotype; all images captured at 20X magnification.