Table 3.
Adjusteda ORs and 95% CI of high phobic anxiety (CCI ≥ 4) by bone lead tertile.
| All women (n = 599; 1,100 assessmentsb) | Premenopausal or postmenopausal on HRTc (n = 140; 261 assessments) | |||||||
|---|---|---|---|---|---|---|---|---|
| Lead biomarkers | CCI ≥ 4 (yes/no) | OR (95% CI) | CCI ≥ 4 (yes/no) | OR (95% CI) | ||||
| Tibia lead tertile (μg/g) | ||||||||
| < 7.0 | 78/288 | Reference | 11/73 | Reference | ||||
| 7.0–11.5 | 66/265 | 0.84 (0.54, 1.32) | 21/83 | 1.52 (0.60, 3.82) | ||||
| > 11.5 | 100/303 | 1.10 (0.73, 1.64) | 20/53 | 2.79 (1.02, 7.59) | ||||
| p-Trend | 0.62 | 0.05 | ||||||
| Patella lead tertile (μg/g) | ||||||||
| < 8.5 | 80/270 | Reference | 16/71 | Reference | ||||
| 8.5–14.5 | 78/254 | 0.96 (0.63, 1.47) | 26/64 | 1.16 (0.41, 3.28) | ||||
| > 14.5 | 86/330 | 0.75 (0.49, 1.16) | 10/74 | 0.23 (0.07, 0.69) | ||||
| p-Trend | 0.17 | 0.003 | ||||||
| aAdjusted for substudy group, age at bone lead and at CCI measurement, education, husband’s education, alcohol consumption, pack-years of smoking, and employment status at CCI measurement. bOnly 1,098 for patella lead analyses because of missing patella lead data. cWomen who were either premenopausal at the time of bone lead measurement (n = 45) or consistently on HRT between menopause and bone lead measurement (n = 97). | ||||||||