Table 1.
Descriptive information of the women and biomarkers analyzed.a
| Variable | Median | 5th–95th percentile | ||
|---|---|---|---|---|
| Age (years) | 34 | 18–64 | ||
| Body weight (kg) | 57.0 | 44.0–79.9 | ||
| Height (cm) | 152 | 144–161 | ||
| BMI (kg/m2) | 24.7 | 18.8–35.0 | ||
| Blood hemoglobin (g/L) | 155 | 130–180 | ||
| Urinary creatinine (g/L)b | 0.90 | 0.52–1.4 | ||
| Coca chewing (%) | 46.5 | |||
| Methylation (%) | ||||
| LINE1c | 86.2 | 83.5–89.3 | ||
| p16d | 3.4 | 1.7–5.8 | ||
| MLH1e | 4.2 | 1.2–7.1 | ||
| Blood measures | ||||
| Cadmium (μg/L) | 0.36 | 0.20–0.76 | ||
| Selenium (μg/L) | 176 | 150–221 | ||
| Zinc (mg/L) | 6.8 | 5.5–8.2 | ||
| Urinary measures | ||||
| Cadmium (μg/L)b | 0.23 | 0.091–0.70 | ||
| Arsenic (μg/L)b | 230 | 21–545 | ||
| Boron (mg/L)b | 14.6 | 2.6–27.9 | ||
| Cesium (μg/L)b | 470 | 26.1–880 | ||
| Lithium (mg/L)b | 3.9 | 0.27–10.4 | ||
| an = 202 subjects, except for creatinine (n = 194) and blood selenium (n = 201) analyses. bAdjusted for specific gravity of urine (1.020 g/mL). cAverage of relative amounts of methylated cytosines in four CpGs, positions 305–331, GenBank accession no. X58075. dAverage of relative amounts of methylated cytosines in seven CpGs, positions 148–174, accession no. L27211. eAverage of relative amounts of methylated cytosines in four CpGs, positions –209 to –188, accession no. U07418. | ||||