Table 2.
Genotyping and allele frequency of ORAI1 gene in patients with breast cancer with or without nodal involvement.
| Positive (%) | Negative (%) | Positive (%) | Negative (%) | Dominant | Recessive | Allelic | |||
|---|---|---|---|---|---|---|---|---|---|
| Genotype | (n = 130) | (n = 248) | Allele | (n = 130) | (n = 248) | P value | P value | P value | |
| rs12320939 | TT | 18 (14.2) | 57 (23.6) | T | 117 (46.1) | 224 (46.3) | 0.0688 | 0.0334* | 0.9550 |
| TG | 81 (63.8) | 110 (45.4) | G | 137 (53.9) | 260 (53.7) | ||||
| GG | 28 (22.0) | 75 (31.0) | |||||||
| rs12313273 | CC | 7 (5.5) | 15 (6.2) | C | 71 (27.7) | 121 (25.0) | 0.2551 | 0.7777 | 0.4196 |
| CT | 57 (44.5) | 91 (37.6) | T | 185 (72.3) | 363 (75.0) | ||||
| TT | 64 (50.0) | 136 (56.2) | |||||||
| rs7135617 | TT | 17 (13.7) | 41 (17.4) | T | 108 (43.5) | 198 (42.1) | 0.1997 | 0.3603 | 0.7143 |
| TG | 74 (59.7) | 116 (49.4) | G | 140 (56.5) | 272 (57.9) | ||||
| GG | 33 (26.6) | 78 (33.2) | |||||||
| rs6486795 | CC | 12 (9.5) | 29 (12.2) | C | 94 (37.0) | 169 (26.2) | 0.2843 | 0.4304 | 0.6869 |
| CT | 70 (55.1) | 111 (46.6) | T | 160 (63.0) | 307 (73.8) | ||||
| TT | 45 (35.4) | 98 (41.2) | |||||||
| rs712853 | CC | 11 (8.6) | 25 (10.3) | C | 81 (31.6) | 160 (33.1) | 0.8399 | 0.5918 | 0.6956 |
| CT | 59 (46.1) | 110 (45.5) | T | 175 (68.4) | 324 (66.9) | ||||
| TT | 58 (45.3) | 107 (44.2) |
*0.01≦P value < 0.05 is labeled in bold. **P value < 0.01 is labeled in bold.