Skip to main content
. 2012 Jun;180(6):2240–2248. doi: 10.1016/j.ajpath.2012.03.008

Figure 3.

Figure 3

Genome copy variation in benign prostate tissues adjacent to cancer predicts prostate cancer relapse. A: Histograms of genome deletion (blue) or amplification (red) of AT no relapse, AT relapse, AT not short PSADT, and AT short PSADT in 23 pairs of human chromosomes. B: ROC curves of AT predicting prostate cancer relapse. The AT samples were separated into a group that relapsed within 5 years of prostatectomy (n = 21) and a group that did not relapse (n = 28). Prediction using gene deletions or amplifications unique to the relapsing group, generated through leave-one-out analysis, was performed to produce the ROC chart. ROC curves of AT predicting prostate cancer short PSADT (C and D). The AT samples were separated into a group that had PSADT within 4 months of prostatectomy (n = 8) and a group that did not (n = 41). Prediction using gene deletions or amplifications unique to the fast-relapsing group, generated through leave-one-out analysis, was performed to produce the ROC chart. Dotted line, random prediction baseline.