Figure 3.

Necrosis is decreased after transplantation of ICAM-1 deficient fatty livers. Mouse livers were transplanted, as described in Section 2. At 8 h postoperatively, necrosis was assessed by H&E histology after sham operation (a), transplantation of wild type (WT) livers (b), and transplantation of ICAM-1 deficient (KO) livers (c). (d) shows necrosis as percent area in liver sections averaged from 5 livers per group. Necrosis in sham-operated WT and KO livers was absent. Bar is 50 μm. *P < 0.05 versus WT grafts.