Figure 4.

Apoptosis is decreased after transplantation of ICAM-1 deficient fatty livers. Mouse livers were transplanted, as described in Section 2. At 8 h postoperatively, TUNEL was assessed in tissue sections after sham operation (a), transplantation of wild type (WT) livers (b), and transplantation of ICAM-1 deficient (KO) livers (c). (d) quantifies the TUNEL-positive cells per high power field (HPF). TUNEL for WT sham was virtually zero and comparable to KO sham, and only KO sham is plotted. Bar is 50 μm. *P < 0.05 versus WT grafts.