Figure 5.

ICAM-1 deficient grafts show decreased leukocyte adherence but unchanged rolling margination after ethanol-induced fatty mouse liver transplantation. Livers were transplanted (LT) or subjected to sham operation (Sham) and visualized by intravital confocal microscopy of rhodamine 6G fluorescence after 4 h, as described in Section 2. Rhodamine 6G-fluorescing leukocytes were scored for slow flow rolling margination (Rollers, (a)) and no flow adherence to sinusoidal walls (Stickers, (b)) as either fold increase versus sham (a) or as absolute number per μm²(b). WT and KO sham groups were comparable, and only the KO sham group is plotted. Individual group size was 4. *P < 0.05 versus WT grafts.