Figure 6.

Thrombin–antithrombin complex (TAT) levels detected in the fluid phase after whole-blood (soluble heparin concentration 1.5 IU ml⁻¹) contact with the heparinized PPy–cellulose membranes and the reference materials. The level of TAT complex generated by the non-heparinized PPy–cellulose membrane was (10 670 ± 1269 µg l⁻¹) and significantly higher than the heparinized composites and the reference materials. This value was omitted in the figure for clarity. No significant difference was found between the heparinized composites and the reference materials. The values represent the mean ± s.e. of the mean from experiments using blood from 10 different donors. (H, heparinized composite; H Red-Ox, heparinized composite after reduction–oxidation cycles; CA, cellulose acetate; RC, regenerated cellulose; PS polysulphone, 0.2 represents 0.2 µm pore size and 0.45 indicates membranes with 0.45 µm pore sizes.)