Fig. 3.

Time series of quantitative Zr-89 cetuximab image slices in mice, from Aerts et al. [39]. Note the blood pool progressively clears as the bilateral HT29 tumors (red arrows) show progressive antibody uptake over time. The mouse was injected with 100 μg of antibody carrying 200 μCi of Zr-89 (protein dose of approximately 3.3 mg/kg), which was sufficient to obtain images out to 5 days post-injection. The scan time was 25 min. Reprinted by permission of the Society of Nuclear Medicine from Aerts et al. [39] (Fig. 2)