Table I.
Mean Physiological Values with Standard Deviations in Tumor and Various Tissues
| V v (n = 5) | V i (n = 5) | |
|---|---|---|
| Tumor | 8.2 ± 1.3 | 170 ± 25 |
| Liver | 55 ± 11 | 72 ± 8.5 |
| Spleen | 117 ± 36 | n.r.a |
| Kidney | 108 ± 28 | 1,200 ± 300b |
| Lung | 214 ± 78 | 270 ± 120 |
| Heart | 49 ± 9 | 190 ± 92 |
| Muscle | 5.4 ± 2.0 | 48 ± 8.0 |
| Fat | 9.3 ± 4.0 | 49 ± 12 |
Vascular volumes (V v) and interstitial volumes (V i) are in microliters per gram. Adapted from Pastuskovas et al. (15)
aVi values are not reported (n.r.) for spleen due to dependence of V i on V v and the spleen’s role in RBC sequestration, which results in calculation of negative values
bRenal V i values are not physiologically accurate due to the kidney’s role in radioactive tracer clearance