Table 2.

Muscle protein metabolism in models of sepsis induced by bacteria administration

Model	Species	Results	Reference
E. coli, i.v. † at 2, 6 and 10 days	Rat	↓muscle mass (SOL, EDL, TA, EPI) ↑protein synthesis in incubated EPI at day 6 ↑proteolysis in incubated EPI at days 2, 6 and 10	Voisin et al. (1996)
S. aureus, i.m. † at 24 h	Mouse	↑proteolysis in incubated GM ↑mRNA for proteasome C5 subunit (GM) ↑chymotrypsin-like enzyme activity (GM)	Khal and Tisdale (2008)

^†sacrifice time after bacteria administration; SOL, m. soleus; TA, m. tibialis anterior; EPI, m. epitrochlearis; EDL, m. extensor digitorum longus; GM, m. gastrocnemius.