. 2012 Jun;93(3):225–233. doi: 10.1111/j.1365-2613.2012.00808.x

Table 2.

Effects of treatment with bark extract of Bathysa cuspidata on lung stereological parameters of Wistar rats with extra-pulmonary acute lung injury induced by paraquat

Groups	Vv [septum] (%)	Vv [space] (%)	Vv [cell] (%)	Sv [epi] (mm²/mm³)
SAL	53.59 ± 3.98^a	46.41 ± 3.99^a	6.23 ± 0.75^a	19.55 ± 3.34^a
PQ	74.55 ± 6.40^b	25.45 ± 6.38^b	10.33 ± 2.90^b	9.96 ± 2.73^b
PQ/VE	72.26 ± 7.23^b	27.74 ± 7.08^b	9.52 ± 2.47^b	11.25 ± 3.79^b
VE	56.01 ± 4.11^a	43.99 ± 3.72^a	6.48 ± 0.81^a	17.25 ± 2.47^a
BCE 400	54.45 ± 5.53^a	45.55 ± 5.41^a	5.98 ± 0.96^a	17.92 ± 1.91^a
PQ/BCE 200	63.14 ± 10.61^b	36.86 ± 10.52^b	6.85 ± 1.63^a	14.16 ± 2.10^b
PQ/BCE 400	55.51 ± 2.12^a	44.49 ± 7.05^a	5.22 ± 1.98^a	18.72 ± 2.17^a

Acute lung injury was induced by a single dose of paraquat (PQ, 30 mg/kg, wt, i.p.), and the animals were treated with extract of Bathysa cuspidata (BCE 200 and 400 mg/kg, wt.) diluted in vehicle DMSO (VE). Control animals received saline (SAL), paraquat (PQ), vehicle DMSO (VE) or BCE 400 mg/kg alone. Vv, volume density; Sv, surface density; septum, alveolar septum; space, alveolar space; epi, epithelium. The data are expressed as means ± SD. Different letters in columns indicate statistical difference between the groups (P < 0.05), and groups that have some common letter do not differ statistically, anova followed by Tukey’s test.