Table 4.
Comparison of demographic and clinical characteristics between mortality and non-mortality group.
| Mortality (n = 10) | Non-mortality (n = 17) | P value | |
|---|---|---|---|
| Demographic characteristics | |||
| Female | 10 (100%) | 15 (88.24%) | 0.387 |
| Age of onset AP (y) | 24.10 ± 12.02 | 28.65 ± 14.07 | 0.123 |
| SLEDAI score at onset of AP | 25.00 ± 9.40 | 19.76 ± 10.61 | 0.065 |
| Number of organs involved | 6.20 ± 1.14 | 5.41 ± 1.73 | 0.167 |
| Intensive therapy of GC/ISA | 4 (40%) | 12 (70.59%) | 0.124 |
|
| |||
| Clinical characteristics | |||
| Fever | 10 (100%) | 11 (64.71%) | 0.042 |
| Mucocutaneous involvement | 6 (60%) | 12 (70.59%) | 0.439 |
| Articular involvement | 6 (60%) | 7 (41.18%) | 0.293 |
| Serositis | 7 (70%) | 8 (47.06%) | 0.226 |
| Neuropsychiatric involvement | 4 (40 %) | 3 (17.65%) | 0.204 |
|
| |||
| Laboratory findings | |||
| Serum amylase∗ | 14.79 ± 17.34 | 8.15 ± 6.03 | 0.241 |
| Serum lipase∗ | 6.46 ± 3.51 | 8.20 ± 5.58 | 0.368 |
| Elevated serum transaminase | 8 (80%) | 10 (58.82%) | 0.244 |
| Hypoalbuminemia | 9 (90%) | 8 (47.06%) | 0.031 |
| Proteinuria | 10 (100%) | 12 (70.59%) | 0.077 |
| Hematuria | 10 (100%) | 7 (41.18%) | 0.002 |
| Granular casts | 7 (70%) | 4 (23.53%) | 0.024 |
| Hyperbilirubinemia | 4 (40%) | 1 (5.88%) | 0.047 |
| Positive anti-dsDNA | 10 (100%) | 14 (82.35%) | 0.232 |
| Positive anti-Sm | 2/8 (25%) | 4/13 (30.77%) | 0.59 |
| Low C3 | 9/9 (100%) | 17/17 (100%) | 1.0 |
| Low C4 | 7/9 (77.78%) | 14/17 (82.35%) | 0.58 |
| Anti-Ro | 3/8 (37.5%) | 10/13 (76.92%) | 0.09 |
| Anti-La | 1/8 (12.5%) | 6/13 (46.15%) | 0.133 |
∗Times in excess of the upper limit of normal (ULN).