Table I.
Baseline characteristics of the patient samples.
| Number of samples (n) (all newly diagnosed AML) | |
|---|---|
| Patients/specimens | 49/57 |
| With protein data | 46/49 |
| AHD | 15 |
| Prior cancers | 12 |
| Cytogenetics | |
| Diploid | 24 |
| chr. 5/7 | 6 |
| Complex | 8 |
| inv 16 | 1 |
| inv 9, t(6;9), +8, +21 | 5 |
| Non-evaluable/IM | 5 |
| FAB | |
| M0 | 6 |
| M1 | 3 |
| M2 | 12 |
| M4 | 14 |
| M5 | 7 |
| M6/M7 | 2 |
| Unknown | 5 |
Samples used for mutation screening and protein expression. Fifty-seven samples from 49 patients, eight patients had specimens from blood and marrow. For 46 of 49 patients, protein expression data was available.
AML, acute myeloid leukaemia; AHD, antedecendent haematological disorder; FAB, French–American–British Classification; chr. 5/7, any abnormality of chromosome 5 or 7; +8/+21, trisomie 8 or 21; IM, insufficient metaphases.