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. Author manuscript; available in PMC: 2012 Jun 28.
Published in final edited form as: Clin Cancer Res. 2010 Mar 9;16(6):1865–1874. doi: 10.1158/1078-0432.CCR-09-2551

Fig. 2.

Fig. 2

Distribution of expression of FOXO3A and phosphoFOXO3A in AML based on source, disease status, and relative to normal CD34+ cells. Top, the ratio of expression between 140 paired blood and marrow specimens is shown. There was no significant difference between the two sources of leukemic blasts. Middle, the ratio of expression between 49 paired diagnosis and relapse specimens is shown. FOXO3A levels were significantly higher in relapse compared with diagnosis, but pFOXO3A levels did not differ. Bottom, comparison of expression distribution histograms of 511 AML samples (gray) relative to 10 normal CD34+ samples (black) is shown. Both FOXO3A and pFOXO3A showed expression levels that were significantly below that of the normal CD34+ cells.