Figure 1. .

Quantification on the protective effect of TUDCA on Lrat^–/– cones. (A) Cones of TUDCA or vehicle injected Lrat^–/– mice (P28) were visualized by labeling cone arrestin in flatmounted retinas. Scale bar = 50 μm. (B) Cone photoreceptors were counted in the ventral, central, and dorsal sections in TUDCA injected Lrat^–/– (n = 8), vehicle-injected Lrat^–/– (n = 6), and untreated WT (n = 5). Data were expressed as the average numbers of cones per mm² (mean ± SEM). Untreated WT mice were included as controls to evaluate the efficacy of TUDCA. ***P < 0.001, NS, not significant.