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. 2012 Jun 5;53(7):3296–3302. doi: 10.1167/iovs.11-8114

Figure 7. .

Figure 7. 

Impact of dexamethasone and bevacizumab on leukocyte infiltration in IL-1β–induced angiogenesis. (A) CD11b staining (green) of IL-1β–implanted corneal sections, treated with IgG, dexamethasone, or bevacizumab. CD11b staining shows CD11b(+) leukocytes in the cornea. (B) Quantitation of the number of CD11b-positive leukocytes (n = 8–10 sections from three or four mice). Bar, 50 μm. (C) Schematic of new leukocyte transmigration rate assay. (D) AO(+) leukocytes and Con A(+) angiogenic vessels in IL-1β–implanted corneas, 2 hours after AO injection, 3 days after pellet implantation. IgG, dexamethasone, or bevacizumab treatments started from day 2. (E) Quantitation of the number of AO(+) leukocytes in angiogenic areas of IL-1β–implanted corneas, 2 hours after AO injection, 3 days after pellet implantation (n = 3–5 from three mice). **P < 0.01.