Table 2.
Major seroreactive proteins of C. burnetii on microarray probed with Q fever patient sera
| Fluorescence intensity | Sensitivitya | ||||||
|---|---|---|---|---|---|---|---|
| Protein | Normal (n = 25) |
Acute early (n = 25) |
Acute late (n = 25) |
Convalescent (n = 6) |
Acute early | Acute late | Convalescent |
| GroEL | 114 ± 84 | 1548 ± 1996 | 3915 ± 3462 | 642 ± 382 | 84% | 88% | 83% |
| YbgF | 104 ± 83 | 752 ± 1308 | 1517 ± 1946 | 1176 ± 1061 | 44% | 72% | 67% |
| RplL | 85 ± 88 | 277 ± 396 | 949 ± 1174 | 185 ± 119 | 20% | 68% | 17% |
| Mip | 137 ± 78 | 324 ± 233 | 611 ± 669 | 237 ± 157 | 44% | 60% | 17% |
| Com1 | 70 ± 84 | 120 ± 326 | 461 ± 525 | 253 ± 176 | 12% | 52% | 50% |
| OmpH | 141 ± 95 | 210 ± 195 | 676 ± 1192 | 398 ± 540 | 20% | 48% | 17% |
| DnaK | 95 ± 91 | 143 ± 122 | 371 ± 480 | 165 ± 105 | 16% | 48% | 17% |
aSensitivity was calculated as the percentage (the number of microarray-positive sera divided by the number of sera of patients with Q fever)