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. 2012 May 29;109(24):E1540-E1547. doi: 10.1073/pnas.1120036109

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Fig. P1. — Top: A model of the water-conducting channel Aquaporin Z (green) superposed with the native crystal structure (red) embedded within the plasma membrane. Bottom: Contact map for Aquaporin Z representing the distance between all possible residue pairs in the 3D protein structure using a 2D matrix. For two residues i and j, element ij of the matrix is filled if the two residues are closer than 8 Å. Contacts predicted using PSICOV are shown in green, whereas those derived from the native crystal structure are shown in red. Folding of the model is guided solely by the predicted contacts.