Table 1.
Modeling targets. Topology indicates the number of transmembrane helices. Contact performance by PSICOV (38) is based on L/2 precision (i.e., top-L/2 predictions for a protein of length L)
Top L/2 contact precision at sequence separation |
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PDB | Protein | Length | Topology | MSA size | Total | 5–9 | 10–22 | > 23 |
1fftC | Ubiquinol Oxidase | 185 | 5 | 6805 | 0.215 | 0.125 | 0.056 | 0.237 |
1gzmA | Rhodopsin | 329 | 7 | 38101 | 0.576 | 0.205 | 0.333 | 0.515 |
1ldiA | Glycerol uptake facilitator | 254 | 6 | 3899 | 0.633 | 0.448 | 0.423 | 0.523 |
1pw4A | Glycerol-3-Phosphate Transporter | 434 | 12 | 82032 | 0.596 | 0.202 | 0.432 | 0.587 |
1xqfA | Ammonia Channel | 362 | 11 | 3177 | 0.670 | 0.469 | 0.667 | 0.571 |
2abmH | Aquaporin Z | 227 | 6 | 4035 | 0.632 | 0.368 | 0.577 | 0.518 |
2b2fA | Ammonium transporter Amt-1 | 391 | 11 | 3188 | 0.694 | 0.500 | 0.674 | 0.577 |
2d2cN | Cytochrome b6f | 202 | 4 | 37253 | 0.373 | 0.125 | 0.286 | 0.265 |
2d57A | Aquaporin-4 | 224 | 6 | 4082 | 0.602 | 0.400 | 0.359 | 0.487 |
2f2bA | Aquaporin Aqpm | 245 | 6 | 3893 | 0.683 | 0.410 | 0.462 | 0.634 |
2feeB | ClC chloride transporter | 441 | 10 | 3516 | 0.457 | 0.099 | 0.143 | 0.417 |
2nq2A | ABC transporter permease HI1471 | 308 | 10 | 8071 | 0.697 | 0.311 | 0.523 | 0.626 |
2nr9A | Protease GlpG | 192 | 6 | 3979 | 0.536 | 0.265 | 0.269 | 0.433 |
2occA | Mitochondrial cytochrome c oxidase | 514 | 12 | 165064 | 0.624 | 0.476 | 0.500 | 0.535 |
2onkC | Molybdate transporter ModBC | 252 | 6 | 62736 | 0.646 | 0.306 | 0.429 | 0.488 |
2q7rA | FLAP protein | 140 | 4 | 479 | 0.239 | 0.000 | 0.036 | 0.268 |
2qfiA | Zinc transporter YiiP | 286 | 6 | 5418 | 0.194 | 0.192 | 0.175 | 0.111 |
2r6gG | Maltose transporter MalFGK | 284 | 6 | 42217 | 0.615 | 0.145 | 0.543 | 0.500 |
2witA | Sodium-betaine symporter BetP | 531 | 12 | 1803 | 0.407 | 0.146 | 0.149 | 0.313 |
2wswA | Carnitine transporter | 508 | 12 | 1827 | 0.405 | 0.167 | 0.128 | 0.331 |
2ydvA | Adenosine receptor A2A | 315 | 7 | 38924 | 0.595 | 0.197 | 0.276 | 0.532 |
2z73A | Rhodopsin | 350 | 7 | 37139 | 0.636 | 0.169 | 0.359 | 0.534 |
3b9wA | RH50 protein | 362 | 11 | 3211 | 0.489 | 0.229 | 0.606 | 0.407 |
3dhwA | Methionine importer MetNI | 203 | 5 | 66018 | 0.343 | 0.128 | 0.105 | 0.349 |
3mk7A | Cytochrome c oxidase, cbb3 type | 466 | 12 | 16147 | 0.308 | 0.130 | 0.250 | 0.291 |
3mktA | MDR efflux pump | 460 | 12 | 10035 | 0.342 | 0.378 | 0.368 | 0.247 |
3pjzA | Potassium uptake protein TrkH | 468 | 12 | 2598 | 0.472 | 0.341 | 0.448 | 0.366 |
3qnqA | Saccharide transporter component ChbC | 432 | 10 | 1967 | 0.560 | 0.257 | 0.211 | 0.413 |