Fig. 3.

Heat map of all genes changed at least twofold on the microarray. A cluster diagram of the 3,602 entities that were statistically significantly changed twofold across the eight microarrays as produced by Partek Genomics Suite software. Blue indicates down-regulation, and red indicates up-regulation. The bracket tree at the top of the diagram demonstrates the similarity between the array data as determined by the clustering algorithm, with the length of the vertical bars being proportional to the degree of dissimilarity. The two arrays from cells expressing the LMP1 DN construct cluster together and then cluster with the pBABE vector control arrays. The expression of the LMP1 DN did not affect the expression pattern of these genes compared with the other arrays.