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A- Representative Western blot image. B- Quantification of Western blot results for pSmad2 and Col1α1. pSmad2/Smad2 ratios and collagen 1α1 production are higher in PF and with smoke exposure, and SB505124 decreases these values, indicating that PF have higher intrinsic TGFβ signaling and that smoke causes TGFβ release. Data are mean+/−SD. *P<0.05, **P<0.01, ***P<0.001.
