Table 1.
Anti-diabetic effects of four waters on alloxan treated male ICR mice
| Water after ALX injection | No. of diabetic mice and of death | Reduction rate | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 6th week | 7th week | 9th weeek | 9th weeek | |||||||
| B. G. L. (mg/dL) | 150–350 | >350 | Death | 150–350 | >350 | Death | 150–350 | >350 | Death | >150 |
| UPW (n = 12) | 2 | 4 | 1 | 5 | 5 | 2 | 2 | 7 | 3 | 100% |
| Hita T. W. (n = 12) | 8 | 0 | 0 | 9 | 2 | 0 | 6 | 3 | 0 | 75.0% |
| Nord. W. (n = 12) | 3 | 0 | 0 | 5 | 2 | 0 | 6 | 2 | 0 | 66.7% |
| CNMW (n = 12) | 4 | 2 | 1 | 3 | 6 | 1 | 4 | 5 | 2 | 90.0% |
CD-1 strain of male ICR mice were administrated four types of water for 9 weeks. ALX injections and blood sampling for B.G.A. were carried out as detailed in the study protocol (Fig. 3). Presented data are the numbers of mice categorized into two hyperglycemic levels (mild diabetes: 150–350 mg/dL and severe diabetes: >350 mg/dL) and of dead mice observed in the 6th, 7th, and 9th week after ALX injection. Percent reductions of diabetes development exhibiting blood glucose levels of greater than 150 mg/mL were calculated at the end of the 9th week. UPW (Control): ultra pure water; Hita T. W.: Hita tenryosui water; Nord. W.: Nordenau water, CNMW: a commercialized brand, B.G.L: blood glucose level (mg/dL)