Table 1.
General Characteristics of the Patients
| Parameter | Value |
|---|---|
| Age (years)* | 51 (39 – 63) 13 – 85 |
| Age at diagnosis (years)* | 47 (35 – 52) (13 – 71) |
| Weight (Kg) | 75 (68 – 88) 49 – 137 |
| Height (m)* | 1.62 (1.56 – 1.70) 1.43 – 1.82 |
| BMI (Kg·m-2)* | 29 (26 – 33) 22 – 46 |
| NC (cm)* | 38 (35 – 40) 32 – 50 |
| Years since diagnosis of acromegaly* | 4 (3 – 10) 0 – 30 |
| Patients subjected to surgerya n (%) | 28 (80) |
| Patients subjected to radiation therapy n (%) | 14 (40) |
| Months receiving octreotide* | 30 (20 – 36) 3 – 62 |
| Controlled patients n (%) | 28 (80) |
| Uncontrolled patients n (%) | 7 (20) |
| Sleep-Related Symptoms | |
| Patients with snoring n (%) | 31 (91) |
| Patients with insomnia n (%) | 26 (76) |
| Patients with observed apneas n (%) | 10 (30) |
| Hypertensionb n (%) | 20 (59) |
| Mallampati score* | 2 (2 – 3) 1 - 4 |
| Tonsillar gradec * | 1 (1 – 2) 0 - 3 |
| Daytime SpO2%* | 93 (92 – 95) 86 - 96 |
| Epworth Scale score* | 10 (6 – 15) 2 – 24 |
| Epworth ≥10 n (%) | 20 (59) |
BMI: body mass index, NC: neck circumference, SpO2%: oxygen saturation by pulse oxymetry.
*
Mean (interquartile Interval) min. – max.
a
Surgery to resect the pituitary adenoma.
b
Medical diagnosis of hypertension; or on antihypertensive treatment; or blood pressure greater than 140/90 mmHg.
c
Grade 0: tonsillectomy; grade 1: tonsils were in the tonsillar fossa; grade 2: tonsils were visible behind the anterior pillars; grade 3: tonsils extended three-quarters of the way to the midline; grade 4: tonsils were completely obstructing the airway [25].