TABLE 5C.

Neonatal behaviors in the MOUSE (oral and sc)

						Magnitude of Dose Tested, mg/kg-day
Author	Test	Age and Route of Exposure	Age of Testing	Sample Size Per Dose Level (Yes/No litter is unit)	Measure	1.0	3.0	6.0
Venerosi et al., 2009	Ultrasonic vocalization 4-min Automated confirmed by observational detection	GD15–18 ORAL Peanut Oil	PND 4, 7,10	1 male/litter; 15 litters/group Yes, litter is unit	# calls			M0 PND4&7 M↓ PND10
					Duration of calls			M0 PND4&7 M↓ PND10
					frequency			M0 PND4&7 M↑ PND10
Ricceri et al., 2003	Ultrasonic vocalization 3-min Not blind	PND1–4 SC DMSO	PND 5, 8, 11	10 males and 10 females from unstated # litters Yes, litter is unit Litter was a factor in the statistical analysis	# calls	0a	0
					Interaction with age of testing	0	0
Ricceri et al., 2003	Homing 3-min to reach goal (wood shavings from home cage) Not blind	PND 12 SC DMSO	PND 12	10 males and 10 females from unstated # litters Yes, litter is unit. Litter was a factor in the statistical analysis	Time to reach nest area	0a	(↓)b
					Time spent in nest area	0	0
					Locomotor activity during 5-min test	0	0

^aall entries without “M” and/or “F” indicates analyses is based on males and females combined

^bauthors state no effect, but noted that pups tended to have shorter latencies