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. 2012 Jun 25;122(7):2652–2660. doi: 10.1172/JCI58813

Figure 5. Spirochete remnants persist at the entheses of C3H Myd88–/– mice after antibiotic therapy.

Figure 5

(A) Multiphoton image of Bb914 in patellar tendon (blue) and amorphous GFP deposits at junction of tendon and articular surface (enthesis) of patella (red) of a sham-treated C3H Myd88–/– mouse. Arrow indicates region shown in inset. Scale bar: 30 μm. (B) Enthesis of a ceftriaxone-treated mouse. Arrow indicates region shown in inset. Scale bar: 30 μm. Images were acquired using a ×20 objective and optically zoomed to a scanned field of view of 300 × 300 μm. The objects delineated by arrows in A and B are enlarged 3-fold and 4-fold, respectively, in the corresponding insets. (C) Photo of articular surface of patella with adjacent tendons. Arrows denote regions where images were acquired. Scale bar: 1 mm.