Table 3. Relationship between Th cell subsets and clinical parameters in asthmatics.
Asthmatics | ||||
Pearson correlation(R value) | P value | No. ofparticipants | ||
FeNO | T-bet− GATA-3− RORγt+ FOXP3− | 0.478 | 0.021 | 23 |
T-bet+ GATA-3− RORγt+ FOXP3− | 0.478 | 0.021 | 23 | |
T-bet− GATA-3− RORγt+ FOXP3+ | 0.482 | 0.020 | 23 | |
FEV1% reversibility | T-bet− GATA-3+ RORγt− FOXP3− | 0.760 | 0.0005 | 22 |
T-bet+ GATA-3+ RORγt− FOXP3− | 0.591 | 0.004 | 22 | |
T-bet+ GATA-3+ RORγt− FOXP3+ | 0.554 | 0.007 | 22 | |
EOS high asthmatics | ||||
FeNO | T-bet− GATA-3− RORγt+ FOXP3− | 0.763 | 0.006 | 11 |
T-bet+ GATA-3− RORγt+ FOXP3− | 0.711 | 0.014 | 11 | |
T-bet− GATA-3− RORγt+ FOXP3+ | 0.669 | 0.024 | 11 | |
FEV1% reversibility | T-bet− GATA-3+ RORγt− FOXP3− | 0.868 | 0.001 | 10 |
T-bet+ GATA-3+ RORγt− FOXP3− | 0.651 | 0.042 | 10 | |
T-bet+ GATA-3+ RORγt− FOXP3+ | 0.599 | ns | 10 | |
EOS low asthmatics | ||||
FeNO | T-bet− GATA-3− RORγt+ FOXP3− | 0.084 | ns | 12 |
T-bet+ GATA-3− RORγt+ FOXP3− | 0.032 | ns | 12 | |
T-bet− GATA-3− RORγt+ FOXP3+ | 0.317 | ns | 12 | |
FEV1% reversibility | T-bet− GATA-3+ RORγt− FOXP3− | −0.295 | ns | 12 |
T-bet+ GATA-3+ RORγt− FOXP3− | −0.493 | ns | 12 | |
T-bet+ GATA-3+ RORγt− FOXP3+ | −0.036 | ns | 12 |
Bold lettering highlights the transcription factor of interest.