Figure 2. Structural properties of the unfolded state as a function of cutoff length.

Panel (a) shows the average radius of gyration in the unfolded state (solid lines) and in molten globule (MG) conformations (dashed lines), where MG conformations are defined as unfolded conformations not containing any secondary structure elements. Panel (b) shows the average number of helical residues in the unfolded state, calculated using STRIDE [39]. Error bars represent the standard error of the mean estimated using blocking.