Table 1. Basic demographic and clinical characteristics of MDD patients with or without melancholia.
The whole sample(n = 1,178) | Nonmelancholic(n = 549) | Melancholic(n = 629) | Statistics a | ||||||
O.R. | 95% CI | P | |||||||
N | % | N | % | N | % | ||||
Male | 385 | 32.7 | 154 | 28.1 | 231 | 36.7 | 1.6 | 1.3, 2.1 | <0.001 |
Married/cohabitating | 824 | 69.9 | 379 | 69.0 | 445 | 70.7 | 1.1 | 0.8, 1.5 | 0.5 |
Employed | 812 | 68.9 | 406 | 74.0 | 406 | 64.5 | 0.7 | 0.5, 0.9 | 0.004 |
Education | |||||||||
Primary and junior secondary school | 356 | 30.2 | 150 | 27.3 | 206 | 32.8 | 1.0 | –- | –- |
Senior secondary school | 312 | 26.5 | 137 | 25.0 | 175 | 27.8 | 1.0 | 0.7, 1.4 | 0.8 |
College and university | 465 | 39.5 | 241 | 43.9 | 224 | 35.6 | 0.8 | 0.5, 1.1 | 0.1 |
Postgraduate | 45 | 3.8 | 21 | 3.8 | 24 | 3.8 | 1.0 | 0.5, 1.9 | 0.9 |
Depressive episodes with increased appetite and sleep and weight gain | 179 | 15.2 | 90 | 16.4 | 89 | 14.1 | 0.9 | 0.6, 1.2 | 0.4 |
Depressive episodes with suicidal ideation and/or attempts | 665 | 56.5 | 304 | 55.4 | 361 | 57.4 | 1.3 | 1.004, 1.6 | 0.047 |
Depressive episodes with psychotic symptoms | 158 | 13.4 | 67 | 12.2 | 91 | 14.5 | 1.3 | 0.9, 1.9 | 0.1 |
Seasonal depressive episodes | 134 | 11.4 | 56 | 10.2 | 78 | 12.4 | 1.7 | 1.2, 2.6 | 0.008 |
Family history of psychiatric disorders | 203 | 17.2 | 114 | 20.8 | 89 | 14.1 | 0.6 | 0.5, 0.9 | 0.004 |
Any use of antidepressants | 820 | 69.9 | 412 | 75.0 | 408 | 64.9 | 0.6 | 0.5, 0.8 | <0.001 |
Any use of antipsychotics | 226 | 19.2 | 104 | 18.9 | 122 | 19.4 | 1.1 | 0.8, 1.5 | 0.4 |
Any use of mood stabilizers | 44 | 3.7 | 28 | 5.1 | 16 | 2.5 | 0.6 | 0.3, 1.1 | 0.1 |
Any use of benzodiazepines | 192 | 16.3 | 77 | 14.0 | 115 | 18.3 | 1.6 | 1.1, 2.2 | 0.01 |
Mean | SD | Mean | SD | Mean | SD | ||||
Age (years) | 40.5 | 12.8 | 40.29 | 12.6 | 40.8 | 13.1 | 1.0 | 0.9, 1.01 | 0.6 |
Age at onset (years) | 34.6 | 12.5 | 33.9 | 11.9 | 35.3 | 13.0 | 1.0 | 0.9, 1.03 | 0.2 |
Lifetime depressive episodes | 1.9 | 2.6 | 2.2 | 2.9 | 1.6 | 2.2 | 0.9 | 0.87, 0.98 | 0.005 |
multiple logistic regression analyses with the nonmelancholic cohort as the reference group.