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. 2012 Jun 29;7(6):e39840. doi: 10.1371/journal.pone.0039840

Table 1. Basic demographic and clinical characteristics of MDD patients with or without melancholia.

The whole sample(n = 1,178) Nonmelancholic(n = 549) Melancholic(n = 629) Statistics a
O.R. 95% CI P
N % N % N %
Male 385 32.7 154 28.1 231 36.7 1.6 1.3, 2.1 <0.001
Married/cohabitating 824 69.9 379 69.0 445 70.7 1.1 0.8, 1.5 0.5
Employed 812 68.9 406 74.0 406 64.5 0.7 0.5, 0.9 0.004
Education
Primary and junior secondary school 356 30.2 150 27.3 206 32.8 1.0 –- –-
Senior secondary school 312 26.5 137 25.0 175 27.8 1.0 0.7, 1.4 0.8
College and university 465 39.5 241 43.9 224 35.6 0.8 0.5, 1.1 0.1
Postgraduate 45 3.8 21 3.8 24 3.8 1.0 0.5, 1.9 0.9
Depressive episodes with increased appetite and sleep and weight gain 179 15.2 90 16.4 89 14.1 0.9 0.6, 1.2 0.4
Depressive episodes with suicidal ideation and/or attempts 665 56.5 304 55.4 361 57.4 1.3 1.004, 1.6 0.047
Depressive episodes with psychotic symptoms 158 13.4 67 12.2 91 14.5 1.3 0.9, 1.9 0.1
Seasonal depressive episodes 134 11.4 56 10.2 78 12.4 1.7 1.2, 2.6 0.008
Family history of psychiatric disorders 203 17.2 114 20.8 89 14.1 0.6 0.5, 0.9 0.004
Any use of antidepressants 820 69.9 412 75.0 408 64.9 0.6 0.5, 0.8 <0.001
Any use of antipsychotics 226 19.2 104 18.9 122 19.4 1.1 0.8, 1.5 0.4
Any use of mood stabilizers 44 3.7 28 5.1 16 2.5 0.6 0.3, 1.1 0.1
Any use of benzodiazepines 192 16.3 77 14.0 115 18.3 1.6 1.1, 2.2 0.01
Mean SD Mean SD Mean SD
Age (years) 40.5 12.8 40.29 12.6 40.8 13.1 1.0 0.9, 1.01 0.6
Age at onset (years) 34.6 12.5 33.9 11.9 35.3 13.0 1.0 0.9, 1.03 0.2
Lifetime depressive episodes 1.9 2.6 2.2 2.9 1.6 2.2 0.9 0.87, 0.98 0.005
a

multiple logistic regression analyses with the nonmelancholic cohort as the reference group.