Table 2. The C-terminal amino acids of TM0476 are like those of several confirmed porins.

	C-terminal amino acids (N → C)
Protein	10	9	8	7	6	5	4	3	2	1
TM0476 (T. maritima)	Y	L	Y	L	K	A	S	V	A	F
PhoE (S. enterica)	I	V	A	I	G	L	T	Y	Q	F
PhoE (E. coli)	I	V	A	V	G	M	T	Y	Q	F
OmpF (E. coli)	T	V	A	V	G	I	V	Y	Q	F
OmpC (E. coli)	I	V	A	L	G	L	V	Y	Q	F

Position 1 indicates the C-terminal amino acid. Hydrophobic residues are boldface. All porins shown possess the essential terminal phenylalanine and hydrophobic residues at positions 3, 5, 7 and 9.